By There has been growing concern about the potential link between paracetamol (acetaminophen) use during pregnancy and the increased risk of neurodevelopmental disorders in children, such as autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD). Paracetamol is widely used as a pain reliever and fever reducer, and it is considered one of the safest medications during pregnancy. However, emerging research suggests a possible association that warrants further investigation.
One key concern is that paracetamol may cross the placental barrier, exposing the developing fetus to its effects. This exposure could potentially disrupt brain development, leading to alterations in cognitive and behavioral outcomes. Several observational studies have found that prolonged or high-dose use of paracetamol during pregnancy may be linked to a higher likelihood of children developing ASD and ADHD symptoms. These findings suggest that paracetamol might interfere with hormonal or inflammatory processes critical for brain development.
However, it is essential to approach these findings cautiously. Most studies have not established a direct causal relationship, and factors such as maternal health conditions, environmental influences, and genetic predisposition may also play significant roles. Additionally, paracetamol remains a recommended treatment for fever during pregnancy, as untreated fever can pose risks to both the mother and the fetus.
Healthcare professionals advise pregnant women to use paracetamol only when necessary and for the shortest duration possible. It is always best for expectant mothers to consult with their healthcare provider before taking any medication. Ongoing research will likely provide more clarity on the long-term effects of paracetamol use during pregnancy and its potential role in neurodevelopmental outcomes.
